Prostate Specific Antigen antibody

Catalog No. ABIN7882062

This Mouse Monoclonal antibody specifically detects Prostate Specific Antigen in IHC (p) and IF. It exhibits reactivity toward Human.

Quick Overview for Prostate Specific Antigen antibody (ABIN7882062)

Target: Prostate Specific Antigen (PSA)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prostate Specific Antigen antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: 3E6-

Product Details anti-Prostate Specific Antigen Antibody

Purpose: PSA Antibody / Prostate Specific Antigen

Purification: Protein G affinity chromatography

Immunogen: Human Prostate Specific Antigen was used as the immunogen for the PSA antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the PSA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the PSA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Alternative Name: PSA

Background: Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.

UniProt: P07288

Pathways: Complement System