Retinoblastoma Protein (Rb) antibody

Catalog No. ABIN7882157

The Rabbit Monoclonal anti-Retinoblastoma Protein (Rb) antibody (Clone BHC-18) (ABIN7882157) specifically detects Retinoblastoma Protein (Rb) in WB. The antibody is reactive with Human samples.

Quick Overview for Retinoblastoma Protein (Rb) antibody (ABIN7882157)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Retinoblastoma Protein (Rb) antibody is un-conjugated

Application: Western Blotting (WB)

Clone: BHC-18

Product Details anti-Retinoblastoma Protein (Rb) Antibody

Purpose: Retinoblastoma Antibody / Rb1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Retinoblastoma / Rb was used as the immunogen for the Retinoblastoma antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Retinoblastoma antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Retinoblastoma antibody at -20oC.

Target Details for Retinoblastoma Protein (Rb)

Target: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Alternative Name: Retinoblastoma

Background: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [RefSeq]

UniProt: P06400

Pathways: Mitotic G1-G1/S Phases