SELPLG antibody

Catalog No. ABIN7882228

The Mouse Monoclonal anti-SELPLG antibody is suitable to detect SELPLG in samples from Human. It has been validated for FACS and IF.

Quick Overview for SELPLG antibody (ABIN7882228)

Target: SELPLG (Selectin P Ligand (SELPLG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SELPLG antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Grade: Carrier-free

Clone: PSGL1-1567

Product Details anti-SELPLG Antibody

Purpose: CD162 Antibody / PSGL-1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant human PSGL-1 /CD162 protein was used as the immunogen for the CD162 antibody.

Isotype: IgM, kappa

Application Details

Application Notes: Optimal dilution of the CD162 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the CD162 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Alternative Name: CD162

Background: CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.

UniProt: Q14242