Septin 5 antibody

Catalog No. ABIN7882234

The Rabbit Polyclonal anti-Septin 5 antibody is suitable to detect Septin 5 in samples from Human and Rat. It has been validated for WB and FACS.

Quick Overview for Septin 5 antibody (ABIN7882234)

Target: Septin 5 (SEPT5)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Septin 5 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Septin 5 Antibody

Purpose: SEPT5 Antibody / Septin 5

Sequence: HYENYRAHCI QQMTSKLTQD

Purification: Antigen affinity purified

Immunogen: Amino acids HYENYRAHCIQQMTSKLTQD were used as the immunogen for the SEPT5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SEPT5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SEPT5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Septin 5

Target: Septin 5 (SEPT5)

Alternative Name: SEPT5

Background: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis