The Rabbit Monoclonal anti-Thrombomodulin antibody is suitable to detect Thrombomodulin in samples from Human. It has been validated for WB and IHC (p).
THBD
Reactivity: Human
WB, FACS, IF
Host: Rabbit
Polyclonal
RB56919
unconjugated
Application Notes
Optimal dilution of the CD141 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Buffer
Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store the CD141 antibody at -20oC.
Target
Thrombomodulin (THBD)
Alternative Name
CD141
Background
The protein encoded by the intronless THBD gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [RefSeq]