TIA1 antibody

Catalog No. ABIN7882490

The Goat Polyclonal anti-TIA1 antibody (ABIN7882490) specifically detects TIA1 in WB, IF, ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TIA1 antibody (ABIN7882490)

Target: TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TIA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TIA1 Antibody

Purpose: TIA1 Antibody / T-Cell Intracellular Antigen-1

Sequence: PKSTYESNTK Q

Purification: Antigen affinity

Immunogen: Amino acids PKSTYESNTKQ were used as the immunogen for this TIA1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the TIA1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X TBS, pH 7.3, with 0.5 % BSA (US sourced) and 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store the TIA1 antibody at -20oC.

Target Details for TIA1

Target: TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Alternative Name: TIA1

Background: T-Cell Intracellular Antigen-1 (TIA1) is involved in regulating gene expression and has been found to be essential for the maintenance of T-cell homeostasis. Research has shown that TIA1 is involved in alternative splicing and mRNA degradation, processes that are essential for the proper functioning of T-cells. In addition, TIA1 has been shown to play a role in the regulation of immune responses and inflammation. TIA1 also plays a role in the response to stress. When T-cells are exposed to stress, TIA1 relocalizes to stress granules and helps to regulate the translation of stress-induced mRNAs. This process is essential for the survival of T-cells under stress conditions.

UniProt: P31483