VAV2 antibody

Catalog No. ABIN7882670

The Rabbit Polyclonal anti-VAV2 antibody (ABIN7882670) specifically detects VAV2 in WB. The antibody is reactive with Human samples.

Quick Overview for VAV2 antibody (ABIN7882670)

Target: VAV2 (Vav 2 Guanine Nucleotide Exchange Factor (VAV2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAV2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VAV2 Antibody

Purpose: VAV2 Antibody (N-Terminal Region)

Purification: Antigen affinity

Immunogen: A portion of amino acids 123--157 from human VAV2 was used as the immunogen for the VAV2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the VAV2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the VAV2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for VAV2

Target: VAV2 (Vav 2 Guanine Nucleotide Exchange Factor (VAV2))

Alternative Name: VAV2

Background: Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). [UniProt]

UniProt: P52735

Pathways: Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway