Recombinant COPS8 antibody

Catalog No. ABIN7938096

The Rabbit Monoclonal anti-COPS8 antibody (Clone 240195B1) (ABIN7938096) specifically detects COPS8 in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Recombinant COPS8 antibody (ABIN7938096)

Target: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This COPS8 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 240195B1

Product Details anti-COPS8 Antibody

Purpose: COPS8 antibody (rAb), 100 μg (Clone 240195B1)

Purification: Protein A Chromatography

Immunogen: This antibody was raised against the COPS8 fusion protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:5000-1:50000 dilution

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS, pH 7.3, with 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Storage: -20 °C

Storage Comment: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Expiry Date: 24 months

Target Details for COPS8

Target: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Alternative Name: COPS8

Background:

Background_Plain: COPS8 is one of the eight subunits of COPS8 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COPS8 signalosome is like that of the 19S regulatory particle of 26S proteasome. COPS8 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases.

Aliases: CSN8, SGN8, COP9 signalosome subunit 8

Molecular Weight: 23 kDa

Pathways: Cell Division Cycle