ACAA2 antibody (Middle Region) (FITC)

Catalog No. ABIN7965434

The Rabbit Polyclonal anti-ACAA2 antibody is suitable to detect ACAA2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for ACAA2 antibody (Middle Region) (FITC) (ABIN7965434)

Target: ACAA2 (Acetyl-CoA Acyltransferase 2 (ACAA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAA2 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-ACAA2 Antibody (FITC)

Binding Specificity: Middle Region

Purpose: Anti-ACAA2 Antibody FITC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by one amino acid,and from the related rat sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ACAA2, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ACAA2

Target: ACAA2 (Acetyl-CoA Acyltransferase 2 (ACAA2))

Alternative Name: ACAA2

Background:

Background: 3-Ketoacyl-CoA thiolase, mitochondrial, also known as acetyl-Coenzyme A acyltransferase 2, is an acetyl-CoA C-acyltransferase enzyme that in humans is encoded by the ACAA2 gene. The ACAA2 gene encodes a 41.9 kDa protein that is composed of 397 amino acids and contains 88 observed peptides. The encoded protein catalyzes the last step of themitochondrial fatty acid beta oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. Additionally, ACAA2 has been shown to be a functional BNIP3 binding partner, which provides a possible link between fatty acid metabolism and cell apoptosis.

Gene Full Name: acetyl-CoA acyltransferase 2

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

Gene ID: 10449

UniProt: P42765

Pathways: Monocarboxylic Acid Catabolic Process