ADAM19 antibody (N-Term) (Biotin)

Catalog No. ABIN7966287

The Biotin-conjugated Rabbit Polyclonal anti-ADAM19 antibody (ABIN7966287) specifically detects ADAM19 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for ADAM19 antibody (N-Term) (Biotin) (ABIN7966287)

Target: ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM19 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ADAM19 Antibody (Biotin)

Binding Specificity: N-Term

Purpose: Anti-ADAM19 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by one amino acid,and from the related rat sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ADAM19, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADAM19

Target: ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))

Alternative Name: ADAM19

Background:

Background: ADAM19 (A Disintegrin and Metalloproteinase Domain 19), also known as MLTNB, is a human gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Hirohata et al. (1998) used radiation hybrids to map ADAM19 to mouse chromosome 11 and to human chromosome 5q32-q33.

Gene Full Name: ADAM metallopeptidase domain 19

Sequence Similarities: Contains 1 disintegrin domain.

Gene ID: 8728

UniProt: Q9H013