ANAPC2 antibody (AA 51-272) (Fluoro488)

Catalog No. ABIN7968357

The Fluoro488-conjugated Rabbit Polyclonal anti-ANAPC2 antibody (ABIN7968357) specifically detects ANAPC2 in FACS. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for ANAPC2 antibody (AA 51-272) (Fluoro488) (ABIN7968357)

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC2 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-ANAPC2 Antibody (Fluoro488)

Binding Specificity: AA 51-272

Purpose: Anti-ANAPC2 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ANAPC2 recombinant protein (Position: K51-R272).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ANAPC2

Target: ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

Alternative Name: ANAPC2

Background:

Background: Anaphase-promoting complex subunit 2 is an enzyme that in humans is encoded by the ANAPC2 gene. A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.

Gene Full Name: anaphase promoting complex subunit 2

Gene ID: 29882

UniProt: Q9UJX6

Pathways: Regulation of Cell Size