APOC3 antibody (AA 21-99) (Fluoro488)

Catalog No. ABIN7969413

This Rabbit Polyclonal antibody specifically detects APOC3 in FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for APOC3 antibody (AA 21-99) (Fluoro488) (ABIN7969413)

Target: APOC3 (Apolipoprotein C-III (APOC3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOC3 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-APOC3 Antibody (Fluoro488)

Binding Specificity: AA 21-99

Purpose: Anti-Apolipoprotein CIII/APOC3 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: coli-derived human Apolipoprotein CIII recombinant protein (Position: S21-A99). Human Apolipoprotein CIII shares 55.3%,54.3% amino acid (aa) sequence identity with mouse,rat Apolipoprotein CIII,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Apolipoprotein CIII recombinant protein (Position: S21-A99). Human Apolipoprotein CIII shares 55.3% and 54.3% amino acid (aa) sequence identity with mouse and rat Apolipoprotein CIII, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for APOC3

Target: APOC3 (Apolipoprotein C-III (APOC3))

Alternative Name: APOC3

Background:

Background: Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is a component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase, it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

Gene Full Name: apolipoprotein C3

Gene ID: 345

UniProt: P02656

Pathways: Carbohydrate Homeostasis, Lipid Metabolism