Apoptosis Inhibitor 5 antibody (C-Term) (Fluoro488)

Catalog No. ABIN7969490

The Fluoro488-conjugated Rabbit Polyclonal anti-Apoptosis Inhibitor 5 antibody (ABIN7969490) specifically detects Apoptosis Inhibitor 5 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Apoptosis Inhibitor 5 antibody (C-Term) (Fluoro488) (ABIN7969490)

Target: Apoptosis Inhibitor 5 (API5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apoptosis Inhibitor 5 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Apoptosis Inhibitor 5 Antibody (Fluoro488)

Binding Specificity: C-Term

Purpose: Anti-Apoptosis inhibitor 5/API5 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse sequence by one amino acid.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Apoptosis inhibitor 5, different from the related mouse sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Apoptosis Inhibitor 5

Target: Apoptosis Inhibitor 5 (API5)

Alternative Name: API5

Background:

Background: Many growth factors and cytokines act as cellular survival factors by preventing programmed cell death (apoptosis). Apoptosis inhibitor 5 (API5) is an antiapoptotic factor which may have a role in protein assembly. The API5 gene to chromosome 11p12 based on an alignment of the API5 sequence with the genomic sequence It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription.

Gene Full Name: apoptosis inhibitor 5

Sequence Similarities: Belongs to the API5 family.

Gene ID: 8539

UniProt: Q9BZZ5

Pathways: Growth Factor Binding