CDK12 antibody (AA 1147-1439) (Fluoro488)

Catalog No. ABIN7977661

The Rabbit Polyclonal anti-CDK12 antibody is suitable to detect CDK12 in samples from Human. It has been validated for FACS.

Quick Overview for CDK12 antibody (AA 1147-1439) (Fluoro488) (ABIN7977661)

Target: CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK12 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-CDK12 Antibody (Fluoro488)

Binding Specificity: AA 1147-1439

Purpose: Anti-CDK12 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CDK12 recombinant protein (Position: Q1147-N1439).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CDK12

Target: CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))

Alternative Name: CDK12

Background:

Background: CDK12 cyclin-dependent kinase 12 is a protein kinase that in humans is encoded by the CDK12 gene. This enzyme is a member of cyclin-dependent kinase protein family. CDK12 forms protein complexes with cyclin K (CCNK). The CDK12-CCNK complex acts at the level of RNA polymerase II (RNAPII) to regulate expression of long complex genes, several of which have roles in DNA maintenance and repair.

Gene Full Name: cyclin dependent kinase 12

Gene ID: 51755

UniProt: Q9NYV4