CDK5RAP2 antibody (AA 168-1878) (Biotin)

Catalog No. ABIN7977703

The Rabbit Polyclonal anti-CDK5RAP2 antibody is suitable to detect CDK5RAP2 in samples from Human. It has been validated for ELISA, IHC and WB.

Quick Overview for CDK5RAP2 antibody (AA 168-1878) (Biotin) (ABIN7977703)

Target: CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK5RAP2 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-CDK5RAP2 Antibody (Biotin)

Binding Specificity: AA 168-1878

Purpose: Anti-CDK5RAP2 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CDK5RAP2 recombinant protein (Position: E168-P1878).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDK5RAP2

Target: CDK5RAP2 (CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2))

Alternative Name: CDK5RAP2

Background:

Background: CDK5 regulatory subunit-associated protein 2 is a protein that in humans is encoded by the CDK5RAP2 gene. This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Gene Full Name: CDK5 regulatory subunit associated protein 2

Gene ID: 55755

UniProt: Q96SN8

Pathways: M Phase, SARS-CoV-2 Protein Interactome