CRBN antibody (AA 1-378) (Fluoro550)

Catalog No. ABIN7978202

The Fluoro550-conjugated Rabbit Polyclonal anti-CRBN antibody (ABIN7978202) specifically detects CRBN in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CRBN antibody (AA 1-378) (Fluoro550) (ABIN7978202)

Target: CRBN (Cereblon (CRBN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRBN antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-CRBN Antibody (Fluoro550)

Binding Specificity: AA 1-378

Purpose: Anti-CRBN Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human CRBN shares 95% amino acid (aa) sequence identity with both mouse,rat CRBN.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CRBN recombinant protein (Position: M1-H378). Human CRBN shares 95% amino acid (aa) sequence identity with both mouse and rat CRBN.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CRBN

Target: CRBN (Cereblon (CRBN))

Alternative Name: CRBN

Background:

Background: Cereblon is a protein that in humans is encoded by the CRBN gene. This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: cereblon

Gene ID: 51185

UniProt: Q96SW2