CRBN antibody (AA 1-378)

Catalog No. ABIN7978209

This Rabbit Polyclonal antibody specifically detects CRBN in WB, ELISA, ICC, FACS and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CRBN antibody (AA 1-378) (ABIN7978209)

Target: CRBN (Cereblon (CRBN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRBN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Grade: Carrier-free

Product Details anti-CRBN Antibody

Binding Specificity: AA 1-378

Purpose: Anti-CRBN Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human CRBN shares 95% amino acid (aa) sequence identity with both mouse,rat CRBN.

Characteristics: Anti-CRBN Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CRBN recombinant protein (Position: M1-H378). Human CRBN shares 95% amino acid (aa) sequence identity with both mouse and rat CRBN.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CRBN

Target: CRBN (Cereblon (CRBN))

Alternative Name: CRBN

Background:

Background: Cereblon is a protein that in humans is encoded by the CRBN gene. This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: cereblon

Molecular Weight: 51 kDa

Gene ID: 51185

UniProt: Q96SW2