CCL26 antibody (AA 24-94) (Biotin)

Catalog No. ABIN7978651

The Rabbit Polyclonal anti-CCL26 antibody is suitable to detect CCL26 in samples from Human. It has been validated for WB, IHC and ELISA.

Quick Overview for CCL26 antibody (AA 24-94) (Biotin) (ABIN7978651)

Target: CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL26 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CCL26 Antibody (Biotin)

Binding Specificity: AA 24-94

Purpose: Anti-Eotaxin 3/CCL26 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Eotaxin 3 recombinant protein (Position: T24-L94).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CCL26

Target: CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))

Alternative Name: CCL26

Background:

Background: Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.

Gene Full Name: C-C motif chemokine ligand 26

Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

Gene ID: 10344

UniProt: Q9Y258

Pathways: Regulation of Actin Filament Polymerization