CCL26 antibody (AA 24-94)
Quick Overview for CCL26 antibody (AA 24-94) (ABIN7978661)
Target
See all CCL26 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Binding Specificity
- AA 24-94
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Purpose
- Anti-Eotaxin 3/CCL26 Antibody
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Specificity
- No cross reactivity with other proteins.
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Characteristics
- Anti-Eotaxin 3/CCL26 Antibody. Tested in WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human Eotaxin 3 recombinant protein (Position: T24-L94).
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Isotype
- IgG
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Application Notes
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Expiry Date
- 12 months
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- CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))
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Alternative Name
- CCL26
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Background
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Background: Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.
Gene Full Name: C-C motif chemokine ligand 26
Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.
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Molecular Weight
- 11 kDa
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Gene ID
- 10344
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UniProt
- Q9Y258
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Pathways
- Regulation of Actin Filament Polymerization
Target
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