Chp2 antibody (AA 1-196) (Fluoro488)

Catalog No. ABIN7979709

This Rabbit Polyclonal antibody specifically detects Chp2 in FACS. It exhibits reactivity toward Human.

Quick Overview for Chp2 antibody (AA 1-196) (Fluoro488) (ABIN7979709)

Target: Chp2

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Chp2 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Chp2 Antibody (Fluoro488)

Binding Specificity: AA 1-196

Purpose: Anti-CHP2 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human CHP2 shares 81.6% amino acid (aa) sequence identity with both mouse,rat CHP2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CHP2 recombinant protein (Position: M1-K196). Human CHP2 shares 81.6% amino acid (aa) sequence identity with both mouse and rat CHP2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Chp2

Target: Chp2

Background:

Background: This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520.

Gene Full Name: calcineurin like EF-hand protein 2

Gene ID: 63928

UniProt: O43745