Factor VII antibody (C-Term) (Fluoro488)

Catalog No. ABIN7980788

The Fluoro488-conjugated Rabbit Polyclonal anti-Factor VII antibody (ABIN7980788) specifically detects Factor VII in FACS. The antibody is reactive with Human samples.

Quick Overview for Factor VII antibody (C-Term) (Fluoro488) (ABIN7980788)

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Factor VII antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-Factor VII Antibody (Fluoro488)

Binding Specificity: C-Term

Purpose: Anti-Factor VII/F7 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Factor VII.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Factor VII

Target: Factor VII (F7) (Coagulation Factor VII (F7))

Alternative Name: F7

Background:

Background: F7 (Coagulation Factor VII), also known as proconvertin, is one of the proteins that causes blood to clot in the coagulation cascade. It is an enzyme of the serine protease class. The F7 gene maps to chromosome 13q34 (Millar et al., 2000). Synthesis of factors VII and X, as well as factors II and IX, takes place in the liver and requires vitamin K. Structural homologies of these factors, which are precursors of serine proteases, have been shown (Zur and Nemerson, 1981). Di Bitondo et al. (2002) used < a href=https://www.bosterbio.com/cells/reporter-cell-lines style=color:#ea8d28>reporter gene analysis to show that inclusion of promoter regions of F7 reduced transcription activity in the presence of estrogenic factors. The effect was independent of promoter polymorphic haplotype.

Gene Full Name: coagulation factor VII

Sequence Similarities: Belongs to the peptidase S1 family.

Gene ID: 2155

UniProt: P08709

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling