Girdin antibody (AA 1231-1836) (APC)

Catalog No. ABIN7980936

This Rabbit Polyclonal antibody specifically detects Girdin in FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for Girdin antibody (AA 1231-1836) (APC) (ABIN7980936)

Target: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Girdin antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Girdin Antibody (APC)

Binding Specificity: AA 1231-1836

Purpose: Anti-CCDC88A Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CCDC88A recombinant protein (Position: K1231-D1836).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Girdin

Target: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Alternative Name: CCDC88A

Background:

Background: Girdin is a protein that in humans is encoded by the CCDC88A gene. This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: coiled-coil and HOOK domain protein 88A

Gene ID: 55704

UniProt: Q3V6T2