CRTC3 antibody (AA 116-619) (Fluoro594)

Catalog No. ABIN7981837

The Rabbit Polyclonal anti-CRTC3 antibody is suitable to detect CRTC3 in samples from Human and Monkey. It has been validated for FACS.

Quick Overview for CRTC3 antibody (AA 116-619) (Fluoro594) (ABIN7981837)

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTC3 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-CRTC3 Antibody (Fluoro594)

Binding Specificity: AA 116-619

Purpose: Anti-CRTC3 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CRTC3 recombinant protein (Position: R116-L619).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CRTC3

Target: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Alternative Name: CRTC3

Background:

Background: CREB-regulated transcription coactivator 3 is a protein that in humans is encoded by the CRTC3 gene. This gene is a member of the CREB regulated transcription coactivator gene family. This family regulates CREB-dependent gene transcription in a phosphorylation-independent manner and may be selective for cAMP-responsive genes. The protein encoded by this gene may induce mitochondrial biogenesis and attenuate catecholamine signaling in adipose tissue. A translocation event between this gene and Notch coactivator mastermind-like gene 2, which results in a fusion protein, has been reported in mucoepidermoid carcinomas. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Gene Full Name: CREB regulated transcription coactivator 3

Gene ID: 64784

UniProt: Q6UUV7

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection