Cyclin B2 antibody (AA 23-391) (HRP)

Catalog No. ABIN7982149

The Rabbit Polyclonal anti-Cyclin B2 antibody is suitable to detect Cyclin B2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for Cyclin B2 antibody (AA 23-391) (HRP) (ABIN7982149)

Target: Cyclin B2 (CCNB2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin B2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Cyclin B2 Antibody (HRP)

Binding Specificity: AA 23-391

Purpose: Anti-Cyclin B2/CCNB2 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Cyclin B2/CCNB2 recombinant protein (Position: K23-A391).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cyclin B2

Target: Cyclin B2 (CCNB2)

Alternative Name: CCNB2

Background:

Background: G2/mitotic-specific cyclin-B2 is a protein that in humans is encoded by the CCNB2 gene. This gene is mapped to 15q22.2. Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.

Gene Full Name: cyclin B2

Gene ID: 9133

UniProt: O95067

Pathways: Cell Division Cycle, M Phase