CYGB antibody (AA 1-190) (PE)

Catalog No. ABIN7983516

This Rabbit Polyclonal antibody specifically detects CYGB in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CYGB antibody (AA 1-190) (PE) (ABIN7983516)

Target: CYGB (Cytoglobin (CYGB))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYGB antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-CYGB Antibody (PE)

Binding Specificity: AA 1-190

Purpose: Anti-Cytoglobin/CYGB Antibody PE Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human Cytoglobin shares 95.3%,93.7% amino acid (aa) sequence identity with mouse,rat Cytoglobin,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Cytoglobin recombinant protein (Position: M1-P190). Human Cytoglobin shares 95.3% and 93.7% amino acid (aa) sequence identity with mouse and rat Cytoglobin, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for CYGB

Target: CYGB (Cytoglobin (CYGB))

Alternative Name: CYGB

Background:

Background: Cytoglobin (CYGB), also called HGB or STAP, is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress. The cytoglobin gene is mapped on 17q25.1. The CYGB gene contains 4 exons and spans about 9 kb. Cytoglobin has many elements common to vertebrate globins, including invariant histidine residues, and the amino acids that form the heme pocket share similarity with pentacoordinate myoglobin. In contrast to the high oxygen affinities displayed by most hexacoordinate hemoglobins, the characteristics of CYGB indicate that it can facilitate oxygen transport. Because the oxygen affinity of CYGB is more similar to myoglobin than to neuroglobin, and the oxy form of CYGB resists autooxidation, CYGB is proposed to represent a tissue oxygen reservoir.

Gene Full Name: cytoglobin

Gene ID: 114757

UniProt: Q8WWM9