DEPTOR antibody (AA 22-409) (Fluoro550)

Catalog No. ABIN7984912

The Rabbit Polyclonal anti-DEPTOR antibody is suitable to detect DEPTOR in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for DEPTOR antibody (AA 22-409) (Fluoro550) (ABIN7984912)

Target: DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DEPTOR antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-DEPTOR Antibody (Fluoro550)

Binding Specificity: AA 22-409

Purpose: Anti-DEPDC6/DEPTOR Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human DEPDC6,DEPTOR shares 97.9% amino acid (aa) sequence identity with mouse DEPDC6,DEPTOR.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human DEPDC6/DEPTOR recombinant protein (Position: A22-C409). Human DEPDC6/DEPTOR shares 97.9% amino acid (aa) sequence identity with mouse DEPDC6/DEPTOR.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for DEPTOR

Target: DEPTOR (DEP Domain Containing mTOR-Interacting Protein (DEPTOR))

Alternative Name: DEPTOR

Background:

Background: DEP domain-containing mTOR-interacting protein (DEPTOR) also known as DEP domain-containing protein 6 (DEPDC6) is a protein that in humans is encoded by the DEPTOR gene. Enables phosphatidic acid binding activity and protein serine/threonine kinase inhibitor activity. Involved in several processes, including negative regulation of TOR signaling, negative regulation of cell size, and negative regulation of protein kinase activity. Is active in lysosomal membrane.

Gene Full Name: DEP domain containing MTOR interacting protein

Gene ID: 64798

UniProt: Q8TB45

Pathways: PI3K-Akt Signaling, RTK Signaling, Regulation of Cell Size, BCR Signaling, Warburg Effect