EPO antibody (AA 1-166) (Fluoro488)

Catalog No. ABIN7988426

The Fluoro488-conjugated Rabbit Polyclonal anti-EPO antibody (ABIN7988426) specifically detects EPO in FACS. The antibody is reactive with Human samples.

Quick Overview for EPO antibody (AA 1-166) (Fluoro488) (ABIN7988426)

Target: EPO (Erythropoietin (EPO))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPO antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-EPO Antibody (Fluoro488)

Binding Specificity: AA 1-166

Purpose: Anti-EPO/Erythropoietin Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human EPO recombinant protein (Position: M1-R166).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for EPO

Target: EPO (Erythropoietin (EPO))

Alternative Name: EPO

Target Type: Hormone

Background:

Background: EPO, Erythropoietin, is an acidic glycoprotein hormone with a molecular mass of 34 kD. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow. This gene is mapped to 7q22.1. It is produced by interstitial fibroblasts in the kidney in close association with peritubular capillary and tubular epithelial cells. It is also produced in perisinusoidal cells in the liver. While liver production predominates in the fetal and perinatal period, renal production is predominant during adulthood. As the prime regulator of red cell production, its major functions are to promote erythroid differentiation and to initiate hemoglobin synthesis. It also has other known biological functions. For example, erythropoietin plays an important role in the brain's response to neuronal injury. EPO is also involved in the wound healing process.

Gene Full Name: erythropoietin

Sequence Similarities: Belongs to the EPO/TPO family.

Gene ID: 2056

UniProt: P01588

Pathways: JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity