FANCA antibody (AA 1272-1439) (Fluoro488)

Catalog No. ABIN7989620

The Fluoro488-conjugated Rabbit Polyclonal anti-FANCA antibody (ABIN7989620) specifically detects FANCA in FACS. The antibody is reactive with Rat and Mouse samples.

Quick Overview for FANCA antibody (AA 1272-1439) (Fluoro488) (ABIN7989620)

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCA antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-FANCA Antibody (Fluoro488)

Binding Specificity: AA 1272-1439

Purpose: Anti-Fanca/FAA Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Fanca/FAA recombinant protein (Position: E1272-F1439).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FANCA

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Alternative Name: Fanca

Background:

Background: Fanconi anaemia, complementation group A, also known as FAA, FACA and FANCA, is a protein which in humans is encoded by the FANCA gene. Acts upstream of or within several processes, including gonad development, regulation of CD40 signaling pathway, and regulation of regulatory T cell differentiation. Predicted to be located in nucleoplasm. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including gut, liver, lung, reproductive system, and spleen. Used to study Fanconi anemia complementation group A. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple), acute myeloid leukemia, esophagus squamous cell carcinoma, ovarian disease (multiple), and skin melanoma. Orthologous to human FANCA (FA complementation group A).

Gene Full Name: Fanconi anemia, complementation group A

Gene ID: 14087

UniProt: Q9JL70

Pathways: DNA Damage Repair