FANCA antibody (AA 1272-1439)

Catalog No. ABIN7989628

The Rabbit Polyclonal anti-FANCA antibody is suitable to detect FANCA in samples from Rat and Mouse. It has been validated for WB, ELISA and FACS.

Quick Overview for FANCA antibody (AA 1272-1439) (ABIN7989628)

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-FANCA Antibody

Binding Specificity: AA 1272-1439

Purpose: Anti-Fanca/FAA Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Fanca/FAA Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Fanca/FAA recombinant protein (Position: E1272-F1439).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FANCA

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Alternative Name: Fanca

Background:

Background: Fanconi anaemia, complementation group A, also known as FAA, FACA and FANCA, is a protein which in humans is encoded by the FANCA gene. Acts upstream of or within several processes, including gonad development, regulation of CD40 signaling pathway, and regulation of regulatory T cell differentiation. Predicted to be located in nucleoplasm. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including gut, liver, lung, reproductive system, and spleen. Used to study Fanconi anemia complementation group A. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple), acute myeloid leukemia, esophagus squamous cell carcinoma, ovarian disease (multiple), and skin melanoma. Orthologous to human FANCA (FA complementation group A).

Gene Full Name: Fanconi anemia, complementation group A

Molecular Weight: 180 kDa

Gene ID: 14087

UniProt: Q9JL70

Pathways: DNA Damage Repair