FANCC antibody (AA 1-558) (Fluoro647)

Catalog No. ABIN7989638

The Fluoro647-conjugated Rabbit Polyclonal anti-FANCC antibody (ABIN7989638) specifically detects FANCC in FACS. The antibody is reactive with Human samples.

Quick Overview for FANCC antibody (AA 1-558) (Fluoro647) (ABIN7989638)

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCC antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-FANCC Antibody (Fluoro647)

Binding Specificity: AA 1-558

Purpose: Anti-FANCC Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FANCC recombinant protein (Position: M1-V558).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for FANCC

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Alternative Name: FANCC

Background:

Background: Fanconi anemia group C protein is a protein that in humans is encoded by the FANCC gene. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.

Gene Full Name: FA complementation group C

Gene ID: 2176

UniProt: Q00597

Pathways: DNA Damage Repair