FANCC antibody (AA 1-558)

Catalog No. ABIN7989639

This Rabbit Polyclonal antibody specifically detects FANCC in WB, ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for FANCC antibody (AA 1-558) (ABIN7989639)

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-FANCC Antibody

Binding Specificity: AA 1-558

Purpose: Anti-FANCC Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-FANCC Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FANCC recombinant protein (Position: M1-V558).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FANCC

Target: FANCC (Fanconi Anemia, Complementation Group C (FANCC))

Alternative Name: FANCC

Background:

Background: Fanconi anemia group C protein is a protein that in humans is encoded by the FANCC gene. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C.

Gene Full Name: FA complementation group C

Molecular Weight: 63 kDa

Gene ID: 2176

UniProt: Q00597

Pathways: DNA Damage Repair