FYCO1 antibody (AA 1-1019) (HRP)

Catalog No. ABIN7992061

The Rabbit Polyclonal anti-FYCO1 antibody is suitable to detect FYCO1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for FYCO1 antibody (AA 1-1019) (HRP) (ABIN7992061)

Target: FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FYCO1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FYCO1 Antibody (HRP)

Binding Specificity: AA 1-1019

Purpose: Anti-FYCO1 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human FYCO1 shares 72.2% amino acid (aa) sequence identity with mouse FYCO1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FYCO1 recombinant protein (Position: M1-K1019). Human FYCO1 shares 72.2% amino acid (aa) sequence identity with mouse FYCO1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for FYCO1

Target: FYCO1 (FYVE and Coiled-Coil Domain Containing 1 (FYCO1))

Alternative Name: FYCO1

Background:

Background: The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2).

Gene Full Name: FYVE and coiled-coil domain autophagy adaptor 1

Gene ID: 79443

UniProt: Q9BQS8

Pathways: SARS-CoV-2 Protein Interactome