MCM5 antibody (AA 651-734)

Catalog No. ABIN749648

Product Details anti-MCM5 Antibody

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Binding Specificity: AA 651-734

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MCM5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MCM5

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Alternative Name: MCM5 (MCM5 Products)

Synonyms: 23.m06024 antibody, cdc46 antibody, xmcm5 antibody, CDC46 antibody, P1-CDC46 antibody, Afu5g02520 antibody, NCU01171.1 antibody, AA617332 antibody, AI324988 antibody, AL033333 antibody, Cdc46 antibody, Mcmd5 antibody, mCD46 antibody, mCDC46 antibody, mcm5 antibody, wu:fb34a06 antibody, CG4082 antibody, DmCDC46 antibody, DmCDC465 antibody, DmMCM5 antibody, DmMcm5 antibody, DmeMCM5 antibody, Dmel\\CG4082 antibody, MCM5 antibody, McM5 antibody, PCR4 antibody, DNA replication licensing factor MCM5 antibody, minichromosome maintenance complex component 5 S homeolog antibody, minichromosome maintenance complex component 5 antibody, DNA replication licensing factor Mcm5 antibody, DNA replication licensing factor mcm5 antibody, MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) antibody, minichromosome maintenance complex component 5 L homeolog antibody, Minichromosome maintenance 5 antibody, DNA replication licensing factor mcm-5 antibody, BBOV_IV010040 antibody, mcm5.S antibody, MCM5 antibody, AFUA_5G02520 antibody, NCU01171 antibody, PVX_084615 antibody, LOC5576119 antibody, CpipJ_CPIJ008678 antibody, Bm1_24480 antibody, CMU_022890 antibody, Mcm5 antibody, mcm5 antibody, TP01_0722 antibody, mcm5.L antibody, mcm-5 antibody

Background:

Synonyms: CDC46, P1-CDC46, DNA replication licensing factor MCM5, CDC46 homolog, MCM5

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.

Gene ID: 4174

UniProt: P33992

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA