GATM antibody (AA 1-279) (Fluoro488)

Catalog No. ABIN7994527

The Rabbit Polyclonal anti-GATM antibody is suitable to detect GATM in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for GATM antibody (AA 1-279) (Fluoro488) (ABIN7994527)

Target: GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATM antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-GATM Antibody (Fluoro488)

Binding Specificity: AA 1-279

Purpose: Anti-GATM Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human GATM shares 95.3%,95% amino acid (aa) sequence identity with mouse,rat GATM,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GATM recombinant protein (Position: M1-E279). Human GATM shares 95.3% and 95% amino acid (aa) sequence identity with mouse and rat GATM, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GATM

Target: GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))

Alternative Name: GATM

Background:

Background: Glycine amidinotransferase, mitochondrial is an enzyme that in humans is encoded by the GATM gene. This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by cognitive disability, language impairment, and behavioral disorders.

Gene Full Name: glycine amidinotransferase

Gene ID: 2628

UniProt: P50440