Glypican 3 antibody (AA 32-535) (Fluoro594)

Catalog No. ABIN7994782

The Rabbit Polyclonal anti-Glypican 3 antibody is suitable to detect Glypican 3 in samples from Human. It has been validated for FACS.

Quick Overview for Glypican 3 antibody (AA 32-535) (Fluoro594) (ABIN7994782)

Target: Glypican 3 (GPC3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glypican 3 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-Glypican 3 Antibody (Fluoro594)

Binding Specificity: AA 32-535

Purpose: Anti-Glypican 3/GPC3 Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Glypican 3/GPC3 recombinant protein (Position: D32-A535).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Glypican 3

Target: Glypican 3 (GPC3)

Alternative Name: GPC3

Background:

Background: Glypican-3 is a protein that, in humans, is encoded by the GPC3 gene. It is mapped to Xq26.2. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Gene Full Name: glypican 3

Gene ID: 2719

UniProt: P51654

Pathways: Glycosaminoglycan Metabolic Process