Golgin B1 (GOLGB1) (AA 153-950) antibody (Biotin)

Catalog No. ABIN7994976

This Rabbit Polyclonal antibody specifically detects Golgin B1 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for Golgin B1 (GOLGB1) (AA 153-950) antibody (Biotin) (ABIN7994976)

Target: Golgin B1 (GOLGB1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 153-950

Purpose: Anti-Giantin/GOLGB1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Giantin/GOLGB1 recombinant protein (Position: L153-E950).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Golgin B1 (GOLGB1)

Alternative Name: GOLGB1

Background:

Background: Giantin or Golgin subfamily B member 1 is a protein that in humans is encoded by the GOLGB1 gene. GOLGB1, also known as Giantin and Macrogolgin, is a 360 to 400 kDa member of the Golgin protein family. GOLGB1 is an integral component of the Golgi membrane that associates with the cytoskeleton. It may be involved in both forming intercisternal cross-bridges that mediate stacking in Golgi complexes, and in reorganizing the complexes after they fragment during mitosis. GOLGB1 has also been identified as an autoantigen in chronic rheumatoid arthritis, and in the autoimmune disease Sjoegren syndrome. Human GOLGB1 is 3259 amino acids (aa) in length, and over aa 1596-1702, shares 92 % and 91 % sequence identity with its mouse and rat orthologs, respectively.

Gene Full Name: golgin B1

Gene ID: 2804

UniProt: Q14789

Pathways: SARS-CoV-2 Protein Interactome