GAS6 antibody (AA 488-660) (APC)

Catalog No. ABIN7995247

The Rabbit Polyclonal anti-GAS6 antibody is suitable to detect GAS6 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for GAS6 antibody (AA 488-660) (APC) (ABIN7995247)

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS6 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-GAS6 Antibody (APC)

Binding Specificity: AA 488-660

Purpose: Anti-GAS 6/GAS6 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human GAS 6 shares 79.7%,81.4% amino acid (aa) sequence identity with mouse,rat GAS 6,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GAS 6 recombinant protein (Position: M488-S660). Human GAS 6 shares 79.7% and 81.4% amino acid (aa) sequence identity with mouse and rat GAS 6, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GAS6

Target: GAS6 (Growth Arrest-Specific 6 (GAS6))

Alternative Name: GAS6

Background:

Background: Growth arrest-specific 6, also known as GAS6, is a human gene coding for the Gas6 protein. It is similar to the Protein S with the same domain organization and 43 % amino acid identity. It was originally found as a gene upregulated by growth arrested fibroblasts. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia.

Gene Full Name: growth arrest specific 6

Gene ID: 2621

UniProt: Q14393

Pathways: RTK Signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response