GDF15 antibody (AA 195-308) (Fluoro647)

Catalog No. ABIN7995304

The Rabbit Polyclonal anti-GDF15 antibody is suitable to detect GDF15 in samples from Human. It has been validated for FACS.

Quick Overview for GDF15 antibody (AA 195-308) (Fluoro647) (ABIN7995304)

Target: GDF15 (Growth Differentiation Factor 15 (GDF15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF15 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-GDF15 Antibody (Fluoro647)

Binding Specificity: AA 195-308

Purpose: Anti-GDF15 Antibody Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human GDF15 shares 68.1%,69.2% amino acid (aa) sequence identity with mouse,rat GDF15,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GDF15 recombinant protein (Position: A195-I308). Human GDF15 shares 68.1% and 69.2% amino acid (aa) sequence identity with mouse and rat GDF15, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GDF15

Target: GDF15 (Growth Differentiation Factor 15 (GDF15))

Alternative Name: GDF15

Background:

Background: Growth/differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB. GDF15 mRNA is most abundant in the liver, with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung.

Gene Full Name: growth differentiation factor 15

Gene ID: 9518

UniProt: Q99988

Pathways: SARS-CoV-2 Protein Interactome