GHRH antibody (AA 32-75) (Fluoro550)

Catalog No. ABIN7995529

The Rabbit Polyclonal anti-GHRH antibody is suitable to detect GHRH in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for GHRH antibody (AA 32-75) (Fluoro550) (ABIN7995529)

Target: GHRH (Growth Hormone Releasing Hormone (GHRH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHRH antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-GHRH Antibody (Fluoro550)

Binding Specificity: AA 32-75

Purpose: Anti-GHRH Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GHRH recombinant protein (Position: Y32-L75).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GHRH

Target: GHRH (Growth Hormone Releasing Hormone (GHRH))

Alternative Name: GHRH

Background:

Background: This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Gene Full Name: growth hormone releasing hormone

Gene ID: 2691

UniProt: P01286

Pathways: Hormone Transport, Hormone Activity, cAMP Metabolic Process