HAX1 antibody (AA 1-279) (HRP)

Catalog No. ABIN7996094

The HRP-conjugated Rabbit Polyclonal anti-HAX1 antibody (ABIN7996094) specifically detects HAX1 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for HAX1 antibody (AA 1-279) (HRP) (ABIN7996094)

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAX1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-HAX1 Antibody (HRP)

Binding Specificity: AA 1-279

Purpose: Anti-HAX1 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HAX1 recombinant protein (Position: M1-R279).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HAX1

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Alternative Name: HAX1

Background:

Background: HCLS1-associated protein X-1 is a protein that in humans is encoded by the HAX1 gene. The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: HCLS1 associated protein X-1

Gene ID: 10456

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization