HERC5 antibody (AA 793-1024) (APC)

Catalog No. ABIN7996689

This Rabbit Polyclonal antibody specifically detects HERC5 in FACS. It exhibits reactivity toward Human.

Quick Overview for HERC5 antibody (AA 793-1024) (APC) (ABIN7996689)

Target: HERC5 (Hect Domain and RLD 5 (HERC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC5 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-HERC5 Antibody (APC)

Binding Specificity: AA 793-1024

Purpose: Anti-HERC5 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HERC5 recombinant protein (Position: F793-G1024).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HERC5

Target: HERC5 (Hect Domain and RLD 5 (HERC5))

Alternative Name: HERC5

Background:

Background: Probable E3 ubiquitin-protein ligase HERC5 is an enzyme that in humans is encoded by the HERC5 gene. It is mapped to 4q22.1. This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets.

Gene Full Name: HECT and RLD domain containing E3 ubiquitin protein ligase 5

Gene ID: 51191

UniProt: Q9UII4