HNF1A antibody (AA 431-631) (Fluoro488)

Catalog No. ABIN7997984

The Fluoro488-conjugated Rabbit Polyclonal anti-HNF1A antibody (ABIN7997984) specifically detects HNF1A in FACS. The antibody is reactive with Human samples.

Quick Overview for HNF1A antibody (AA 431-631) (Fluoro488) (ABIN7997984)

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF1A antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-HNF1A Antibody (Fluoro488)

Binding Specificity: AA 431-631

Purpose: Anti-HNF1/HNF1A Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human HNF1 shares 93%,92% amino acid (aa) sequences identity with mouse,rat HNF1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human HNF1 recombinant protein (Position: A431-Q631). Human HNF1 shares 93% and 92% amino acid (aa) sequences identity with mouse and rat HNF1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for HNF1A

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Alternative Name: HNF1A

Background:

Background: HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A or TCF1, is a human gene. It is mapped to chromosome 12q24.3. The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes. HNF1A can function as a dimer. What's more, deletion of the HNF1A activation domains or interruption of the HNF1-binding sites in the LCT promoter resulted in complete loss of transcriptional activity.

Gene Full Name: HNF1 homeobox A

Sequence Similarities: Belongs to the HNF1 homeobox family.

Gene ID: 6927

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis