SREBF chaperone antibody (AA 251-350) (HRP)

Catalog No. ABIN750292

This Rabbit Polyclonal antibody specifically detects SREBF chaperone in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse and Rat.

Quick Overview for SREBF chaperone antibody (AA 251-350) (HRP) (ABIN750292)

Target: SREBF chaperone (SCAP)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF chaperone antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SREBF chaperone Antibody (HRP)

Binding Specificity: AA 251-350

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SCAP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SREBF chaperone

Target: SREBF chaperone (SCAP)

Alternative Name: SCAP/SREBF chaperone protein

Background:

Synonyms: KIAA0199, SCAP, SCAP_HUMAN, SREBF chaperone, SREBF chaperone protein, SREBP cleavage activating protein, SREBP cleavage-activating protein, Sterol regulatory element binding protein cleavage-activating protein, Sterol regulatory element-binding protein cleavage-activating protein.

Background: SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.

Gene ID: 22937

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome