ITGA4 antibody (AA 35-269) (Fluoro550)

Catalog No. ABIN8000344

The Fluoro550-conjugated Rabbit Polyclonal anti-ITGA4 antibody (ABIN8000344) specifically detects ITGA4 in FACS. The antibody is reactive with Human samples.

Quick Overview for ITGA4 antibody (AA 35-269) (Fluoro550) (ABIN8000344)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA4 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-ITGA4 Antibody (Fluoro550)

Binding Specificity: AA 35-269

Purpose: Anti-Integrin Alpha 4/ITGA4 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human ITGA4 shares 85.5% amino acid (aa) sequence identity with mouse ITGA4.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Integrin Alpha 4/ITGA4 recombinant protein (Position: N35-V269). Human ITGA4 shares 85.5% amino acid (aa) sequence identity with mouse ITGA4.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: ITGA4

Background:

Background: ITGA4/Integrin alpha4 is an integrin alpha subunit. It makes up half of the α4β1 lymphocyte homing receptor. The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain. ITGA4 is also mapped to 2q31-q32 by fluorescence in situ hybridization.

Gene Full Name: integrin subunit alpha 4

Gene ID: 3456

UniProt: P13612

Pathways: Integrin Complex