IL-13 antibody (AA 22-131) (Fluoro647)

Catalog No. ABIN8001868

The Fluoro647-conjugated Rabbit Polyclonal anti-IL-13 antibody (ABIN8001868) specifically detects IL-13 in FACS. The antibody is reactive with Rat and Mouse samples.

Quick Overview for IL-13 antibody (AA 22-131) (Fluoro647) (ABIN8001868)

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-13 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-IL-13 Antibody (Fluoro647)

Binding Specificity: AA 22-131

Purpose: Anti-Il13 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Il13 recombinant protein (Position: P22-F131).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL-13

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Alternative Name: Il13

Background:

Background: Interleukin 13 is a protein that in humans is encoded by the IL-13 gene. It is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. Furthermore, this gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Gene Full Name: interleukin 13

Gene ID: 16163

UniProt: P20109

Pathways: JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport