IL-34 antibody (N-Term) (APC)

Catalog No. ABIN8002614

The Rabbit Polyclonal anti-IL-34 antibody is suitable to detect IL-34 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for IL-34 antibody (N-Term) (APC) (ABIN8002614)

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-34 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-IL-34 Antibody (APC)

Binding Specificity: N-Term

Purpose: Anti-IL34 Antibody APC Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Interleukin 34/IL34, which shares 64.2% and 60.7% amino acid (aa) sequence identity with mouse and rat Interleukin 34/IL34, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for IL-34

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Alternative Name: IL34

Background:

Background: Interleukin 34 (IL-34) is a protein belonging to a group of cytokines called interleukins. It was originally identified in humans, by large scale screening of secreted proteins, chimpanzee, murine, rat and chicken interleukin 34 orthologs have also been found. The protein is composed of 241 amino acids, 39 kilodaltons in mass, and forms homodimers. IL-34 increases growth or survival of immune cells known as monocytes, it elicits its activity by binding the Colony stimulating factor 1 receptor. This gene is mapped to 16q22.1.

Gene Full Name: interleukin 34

Gene ID: 146433

UniProt: Q6ZMJ4

Pathways: RTK Signaling