IQGAP2 antibody (AA 1329-1544) (Biotin)

Catalog No. ABIN8003267

This Rabbit Polyclonal antibody specifically detects IQGAP2 in WB, IHC and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for IQGAP2 antibody (AA 1329-1544) (Biotin) (ABIN8003267)

Target: IQGAP2 (IQ Motif Containing GTPase Activating Protein 2 (IQGAP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQGAP2 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-IQGAP2 Antibody (Biotin)

Binding Specificity: AA 1329-1544

Purpose: Anti-IQGAP2 Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IQGAP2 recombinant protein (Position: A1329-Q1544).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IQGAP2

Target: IQGAP2 (IQ Motif Containing GTPase Activating Protein 2 (IQGAP2))

Alternative Name: IQGAP2

Background:

Background: Ras GTPase-activating-like protein IQGAP2 is an enzyme that in humans is encoded by the IQGAP2 gene. This gene encodes a member of the IQGAP family. The encoded protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. This protein interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses. Alternative splicing results in multiple transcript variants.

Gene Full Name: IQ motif containing GTPase activating protein 2

Gene ID: 10788

UniProt: Q13576