JAG1 antibody (AA 994-1218) (Fluoro550)

Catalog No. ABIN8003567

This Rabbit Polyclonal antibody specifically detects JAG1 in FACS. It exhibits reactivity toward Human.

Quick Overview for JAG1 antibody (AA 994-1218) (Fluoro550) (ABIN8003567)

Target: JAG1 (Jagged 1 (JAG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-JAG1 Antibody (Fluoro550)

Binding Specificity: AA 994-1218

Purpose: Anti-Jagged1/JAG1 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Jagged1/JAG1 recombinant protein (Position: A994-V1218).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for JAG1

Target: JAG1 (Jagged 1 (JAG1))

Alternative Name: JAG1

Background:

Background: The JAG1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Gene Full Name: jagged canonical Notch ligand 1

Gene ID: 182

UniProt: P78504

Pathways: Notch Signaling, Stem Cell Maintenance