JAG1 antibody (AA 994-1218) (HRP)

Catalog No. ABIN8003570

This Rabbit Polyclonal antibody specifically detects JAG1 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for JAG1 antibody (AA 994-1218) (HRP) (ABIN8003570)

Target: JAG1 (Jagged 1 (JAG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JAG1 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-JAG1 Antibody (HRP)

Binding Specificity: AA 994-1218

Purpose: Anti-Jagged1/JAG1 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Jagged1/JAG1 recombinant protein (Position: A994-V1218).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for JAG1

Target: JAG1 (Jagged 1 (JAG1))

Alternative Name: JAG1

Background:

Background: The JAG1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Gene Full Name: jagged canonical Notch ligand 1

Gene ID: 182

UniProt: P78504

Pathways: Notch Signaling, Stem Cell Maintenance