LRRC47 antibody (AA 309-583) (Fluoro550)

Catalog No. ABIN8005526

This Rabbit Polyclonal antibody specifically detects LRRC47 in FACS. It exhibits reactivity toward Human.

Quick Overview for LRRC47 antibody (AA 309-583) (Fluoro550) (ABIN8005526)

Target: LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC47 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-LRRC47 Antibody (Fluoro550)

Binding Specificity: AA 309-583

Purpose: Anti-LRRC47 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human LRRC47 recombinant protein (Position: L309-R583).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for LRRC47

Target: LRRC47 (Leucine Rich Repeat Containing 47 (LRRC47))

Alternative Name: LRRC47

Background:

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes Lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Gene Full Name: leucine rich repeat containing 47

Gene ID: 57470

UniProt: Q8N1G4